Franklin's massive review is out in Nature Reviews Microbiology. What an effort. What an overview. Beautiful figures too from Marnix. Great team of authors. Nice!
Tim's paper describing how C- and G- mismatches of target DNA with CRISPR RNA can have such a different outcomes. Nice contribution from Ryan Jackson too!
@Phages, better mutate to G!
TU Delft alumni interested in our work on bacteriophages.
Kurzgezagt makes an episode on phages!
Profielwerkstuk students from three different schools visited our lab to work with bacteriophages.
Single molecule FRET studies at their best: Luuk's paper on DNA reeling by Cas3 published.
With over 100 attendees the symposium on Clinical use of Bacteriophage Therapy was a great success. Thank you Laurent Debarbieux, Rob Lavigne, Martha Clokie, Mzia Kutateladze, Wilbert Sybesma, Jean-Paul Pirnay, and organisers Marc Bonten en Pieter-Jan Haas for making this possible.
Marnix publishes his paper about the effect of Bacteriophage DNA glucosylation on CRISPR interference in Nucleic Acids Research. Well done!
Foreigners and snow: a golden combination!
Our TU Delft team won the grand prize and 8 individual prizes in the overgraduate section of the iGEM Jamboree in Boston. WOW I'm so proud! Superb job team! Thanks supervisors for making this possible. Read about their project and watch the award ceremony here.
Luuk Loeff defended his PhD thesis and got a Cum laude. Committee members: Lucas van Vliet (Dean), Marileen Dogterom, Blake Wiedenheft, Euijeon Woo, Johannes Hohlbein, Cees Dekker (Promotor), Chirlmin Joo (Co-promotor).
Tim got his PhD degree from Wageningen University. Congratulations on this superb job! Glad you were my PhD student.
Committee members: Joyce Lebbink, Blake Wiedenheft, Dolf Weijers, Chirlmin Joo, John van der Oost (promotor), paranimfs Marnix Vlot and Benoit Carreres.
This timelapse over 5 hours shows how antibiotic resistant E. coli bacteria are killed by phage. Perhaps one day the full potential of bacteriophages will be exploited for the treatment of infectious diseases in the Netherlands.
Van der Maasweg 9, 2629 HZ Delft, Netherlands, T +31 15 2783920
Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology
Applied Sciences Building (nr. 58) Office E1.480,
My lab is interested in the interaction between microbes and bacteriophages. We study the mechanisms that bacteria use to protect themselves from infections including CRISPR, and explore the adaptations that viruses have evolved to avoid defence systems. We isolate and engineer bacteriophages for phage therapy applications.
Stan J.J. Brouns, PhD
Kavli Institute of Nanoscience
Applied Sciences Building (nr. 58) Office E1.480
Van der Maasweg 9
2629 HZ Delft
T +31 15 278 3920
HELIX Building (nr. 124)
6708 WE Wageningen
Steun ons bacteriofaag initiatief en doneer aan het onderzoek om een fagenbank in Nederland op te zetten.
E. coli Cascade complex