Welcome to the Brouns lab
News
November 2020
Franklin publishes his paper on self targeting spacers in CRISPR systems, often considered the Achilles heel of CRISPR. Or is it? This organism survived 162 self targeting spacers against 11 prophages in the genome. Great provacative work, as Science should be.
October 2020
Patrick defends his PhD thesis at Utrecht University. Awesome job Dr de Jonge! Smiling both before and after the defense. All the best with your new position in Amsterdam.
October 2020
Jochem publishes his methods paper describing a novel analytical method to analyze the microscopy data of the movement of proteins inside cells. Amazing job!
October 2020
Big day for CRISPR as Emmanuelle and Jennifer receive the Nobel prize for Chemistry for their breakthrough Cas9 findings. Congratulations!
September 2020
Patrick publishes his high-throughput method called Adsorpseq to link unknown bacteriophages to their hosts. How simple, nice and useful can it be!
June 2020
Franklin (on the far left) is starting his own research group in Southampton. What a dream come true for him. Thank you for the amazing time and all the best in the UK.
February 2020
After 3 years, Cristobal is leaving us. We wish you all the best and please stay in touch.
November 2019
Benjamin defends his PhD in style. Congrats with this well-deserved accomplishment.
November 2019
Patrick publishes his paper on BACON domains in crAssphage. Wow that was fast.
November 2019
Jochem publishes his masterpiece about cellular surveillance by Cascade!
November 2019
Amazing, after 8 years the paper is published showing Cascade can be engineered into a genome nuclease. Thanks everyone at Caribou, Peter and Sam. Also thanks to Tim, Selma, Seb, Emiel, Lieuwe for your early contributions.
June 2019
Sebastian and Cristobal publish a paper on conserved sequence motifs in type I-D CRISPR systems. Nice job and thank you reviewer 3 for taking this part out of an earlier story!
April 2019
Brounslab goes karting.
Visiting address
Van der Maasweg 9, 2629 HZ Delft, Netherlands
Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology
Applied Sciences Building (nr. 58) Office E1.480
Host institute
Research interest
My lab is interested in the interaction between microbes and bacteriophages. We study the mechanisms that bacteria use to protect themselves from infections including CRISPR, and explore the adaptations that viruses have evolved to avoid defence systems. We isolate and engineer bacteriophages for phage therapy applications.
Funding
Address
Kavli Institute of Nanoscience
Delft University of Technology
Applied Sciences Building (nr. 58) Office E1.480
Van der Maasweg 9
2629 HZ Delft
Netherlands
Steun ons bacteriofaag initiatief en doneer aan het onderzoek om een fagenbank in Nederland op te zetten.